Comparison of Synchronous Endometrial and Ovarian Cancers versus Primary with Metastasis

Synchronous endometrial and ovarian cancer is uncommon event with the incidence ranging from 2-8.5 % (Castro et al., 2000). Presently, there was no consensus about the definite diagnostic criteria. Most authors usually diagnosed this tumor by pathologic criteria which were proposed by Ulbright and Roth (1985) or Scully et al. (1998). There is no doubt if it had different histology. In contrast, if it had the similar histology, it should be differentiated into 3 categories; 1) synchronous endometrial and ovarian cancer, 2) primary endometrial cancer with ovarian metastasis and 3) primary ovarian cancer with endometrial metastasis. The definite diagnosis is important for determining the exact stage and proper management which would affect the prognosis. Previous studies reported the characteristics in the patients with synchronous endometrial and ovarian cancer occurred typically in young, premenopause, nulliparous and obese. In addition, they usually presented in early stage with low grade histology which influenced excellent prognosis (Sheu et al., 1995; Zaino et al., 2001; Soliman et al., 2004). Generally, it was accepted that the prognosis in these patients is more favorable than stage IIIA